Mensah Research Institute

Evolved Medicine for 21st Century Phys
Mensah Research Institute

Evolved Medicine for 21st Century Phys


Our research

The Mensah Research Institute was founded as a conduit for conducting, supporting, and presenting research efforts that provide scientific evidence of the efficacy of targeted nutrient therapy and other natural approaches to improving brain function, and to enhancing and optimizing mind/body health and balance. Many targeted nutrient therapy treatment protocols are based on decades of research conducted by mental health treatment pioneers such as Dr. Carl Pfeiffer and Dr. William Walsh.  The Mensah Research Institute works to build upon Pfeiffer’s and Walsh’s scientific legacy, further validating the effectiveness of nutrient therapy and identifying new and improved applications for natural protocols that support mind and body.

Dr. A.J. Russo, MRI Director of Research, brings decades of experience and dozens of publications exploring the connections between biochemical imbalances and several mental, psychological and physical disorders.  Today, research conducted at the Mensah Research Institute is focused on far more than just demonstrating that targeted nutrient therapy works.    We are interested in exploring the mind and body at the molecular level, identifying the root causes of disorders and developing and testing natural protocols for addressing those root causes.  Breakthroughs in this area could lead to the eradication of breast cancer and other cancers, auto-immune disease, and several other brain AND body disorders.

In addition, cutting edge, neurological treatments aimed at optimizing brain and body function are being evaluated by the doctors and researchers at MRI.  These treatments look to correct neurological concerns that include Dyslexia, Dyspraxia, Parkinson's Disease, Visual and Auditory Tracking Disorders, and many others.  At Mensah Research Institute, we can clearly see that the future is exciting, the future is full of potential, and the future IS today!


Published articles


  1. Russo AJ, Neville L, Wroge C Low Serum Alpha-1 Antitrypsin (AAT) in Family Members of Individuals with Autism Correlates with PiMZ Genotype.Biomark Insights. 2009 Mar 18;4:45-56. PMID: 19652762 [PubMed] Free PMC Article
  2. Russo AJ et al Low serum myeloperoxidase in autistic children with gastrointestinal disease.Clin Exp Gastroenterol. 2009;2:85-94. Epub 2009 Aug 11. PMID: 21694831 [PubMed] Free PMC Article
  3. Russo AJ et al Decreased Serum Hepatocyte Growth Factor (HGF) in Autistic Children with Severe Gastrointestinal Disease.Biomark Insights. 2009 Nov 27;4:181-90. PMID: 20029653 [PubMed] Free PMC Article
  4. Russo AJ Decreased Serum Cu/Zn SOD Associated with High Copper in Children with Attention Deficit Hyperactivity Disorder (ADHD).J Cent Nerv Syst Dis. 2010 May 4;2:9-14. Print 2010. PMID: 23861627 [PubMed] Free PMC Article
  5. Russo AJ Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy.Nutr Metab Insights. 2010 Jun 17;3:37-42. doi: 10.4137/NMI.S5044. eCollection 2010.PMID: 23966790 [PubMed] Free PMC Article
  6. Russo AJ Decreased Serum Hepatocyte Growth Factor (HGF) in Individuals with Anxiety Increases After Zinc Therapy.Nutr Metab Insights. 2010 Aug 9;3:43-8. doi: 10.4137/NMI.S5495. eCollection 2010. PMID: 23966791 [PubMed] Free PMC Article
  7. Russo AJ Decreased Serum Hepatocyte Growth Factor (HGF) in Individuals with Depression Correlates with Severity of Disease.Biomark Insights. 2010 Aug 3;5:63-7. PMID: 20703323 [PubMed] Free PMC Article
  8. Russo AJ Decreased Serum Hepatocyte Growth Factor (HGF) in Individuals with Bipolar Disorder Normalizes after Zinc and Anti-oxidant Therapy. Nutr Metab Insights. 2010 Oct 19;3:49-55. doi: 10.4137/NMI.S5528. eCollection 2010. PMID: 23946654 [PubMed] Free PMC Article
  9. Russo AJ.Decreased zinc and increased copper in individuals with anxiety.Nutr Metab Insights. 2011 Feb 7;4:1-5. doi: 10.4137/NMI.S6349. eCollection 2011. PMID: 23946656 [PubMed] Free PMC Article
  10. Russo AJ.Analysis of plasma zinc and copper concentration, and perceived symptoms, in individuals with depression, post zinc and anti-oxidant therapy. Nutr Metab Insights. 2011 Apr 17;4:19-27. doi: 10.4137/NMI.S6760. eCollection 2011. PMID: 23946658 [PubMed] Free PMC Article
  11. Russo AJIncreased Copper in Individuals with Autism Normalizes Post Zinc Therapy More Efficiently in Individuals with Concurrent GI Disease.Nutr Metab Insights. 2011 Sep 29;4:49-54. doi: 10.4137/NMI.S6827. eCollection 2011. PMID: 23946661 [PubMed] Free PMC Article
  12. Russo AJ, Devito R. Analysis of Copper and Zinc Plasma Concentration and the Efficacy of Zinc Therapy in Individuals with Asperger’s Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and Autism.Biomark Insights. 2011;6:127-33. doi: 10.4137/BMI.S7286. Epub 2011 Nov 8. PMID: 22174567 [PubMed] Free PMC Article
  13. Russo AJ et al Plasma copper and zinc concentration in individuals with autism correlate with selected symptom severityNutr Metab Insights. 2012 Feb 28;5:41-7. doi: 10.4137/NMI.S8761. Print 2012. PMID:23882147 [PubMed] Free PMC Article
  14. Russo AJ Decreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism.Biomark Insights. 2013 Apr 4;8:35-41. dpi: 10.4137/BMI.S11270. Print 2013. PMID: 23645980 [PubMed] Free PMC Article
  15. Russo AJ Correlation Between Hepatocyte Growth Factor (HGF) and Gamma-Aminobutyric Acid (GABA) Plasma Levels in Autistic Children.Biomark Insights. 2013 Jun 12;8:69-75. doi: 10.4137/BMI.S11448. Print 2013. PMID: 23825437 [PubMed] Free PMC Article
  16. Russo AJ, Pietsch SC. Decreased Hepatocyte Growth Factor (HGF) and Gamma Aminobutyric Acid (GABA) in Individuals with Obsessive-Compulsive Disorder (OCD). Biomark Insights. 2013 Aug 18;8:107-14.doi:10.4137/BMI.S11931. PMID: 24023510 [PubMed] Free PMC Article
  17. Russo AJIncreased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism Spectrum Disorders (ASDs).J Cent Nerv Syst Dis. 2014 Sep 9;6:79-83. doi: 10.4137/JCNSD.S13767. eCollection 2014. PMID: 25249767 [PubMed] Free PMC Article
  18. Russo AJ  Decreased Mitogen Inducible Gene 6 (MIG-6) Associated with Symptom Severity in Children with Autism. Biomark Insights. 2014 Oct 6;9:85-9. doi: 10.4137/BMI.S15218. eCollection 2014. PMID:25342879 Free PMC Article
  19. Russo AJDecreased plasma myeloperoxidase associated with probiotic therapy in autistic children. Clin Med Insights Pediatr. 2015 Feb 3;9:13-7. doi: 10.4137/CMPed.S17901. eCollection 2015. PMID:25674031 Free PMC Article
  20. Russo AJDecreased Phosphorylated Protein Kinase B (Akt) in Individuals with Autism Associated with High Epidermal Growth Factor Receptor (EGFR) and Low Gamma-Aminobutyric Acid (GABA). Biomark Insights. 2015 Oct 14;10:89-94. doi: 10.4137/BMI.S21946. eCollection 2015. PMID:26508828 Free PMC Article
  21. Russo AJ, Anubrolu, L Decreased Oxytocin Associated with high mTOR in Individuals with Autism, JLSB 2016, 3, 119-126. DOI: 10.1234.67/Jlsb.1014
  22. Russo AJ, Anubrolu, L Decreased Phosphorylated ERK 1/2 Related to GABA levels in Bipolar Disorder JLSB 2016, 4, 126-132.
  23. Russo A, Albert M, Judith B. Decreased Phosphorylated CREB and AKT in Individuals with Autism Normalized after Zinc Therapy. Acad J Ped Neonatol. 2017; 5(4): 555721. DOI: 10.19080/AJPN.2017.05.555721.